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Machine Learning Laboratory
 
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Research

Awards

Kay H. Brodersen received a Trainee Abstract Award at HBM 2012 for his work on 'Model-Based Clustering Using Generative Embedding.' Kay will be giving a talk on his results in Beijing on 12 June.

François Cellier received the McLeod Founder's Award of the Society for Modeling and Simulation International.

Spotlight

spotlight



Computational models of brain connectivity, coupled with machine learning algorithms, make it possible to infer neuronal disease mechanisms from non-invasive functional magnetic resonance imaging (fMRI) data in humans. This illustration shows how dynamic systems models can be used for reducing complex (high-dimensional) brain activity data to a simple (low-dimensional) and mechanistically interpretable representation (Brodersen et al., PLoS Comput. Biol. 2011). Please also see the summary on ETH Life.

Our current research is focused on computer vision, computational biology, auditory scene analysis and foundations of machine learning:

Machine Learning und Neuroimaging

   
Neuroimaging
Neuroimaging

The field of neuroimaging has revolutionized the way in which we can study how perceptual and cognitive processes are implemented in the human brain. This is largely due to the development of functional magnetic resonance imaging (fMRI), which makes it possible to record a person’s brain activity over time and relate it to behavioural or clinical measures. We collaborate closely with neuroscientists, psychologists, and behavioural economists, to address some of the fascinating challenges posed by the analysis of brain activity. Specifically, we aim (i) to develop novel multivariate and model-based analysis methods, and (ii) to demonstrate the utility of these methods by applying them to the study of economic decision making in the healthy and the diseased human brain.

 
Project titles:

 
Members:

 - Kay H. Brodersen
 - Alberto Giovanni Busetto
 - Ekaterina I. Lomakina
 - Cheng Soon Ong

Computer Vision

   
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Recent advances in image and video capture have enabled very cheap acquisition of image data. This calls for automatic tools for analysis, categorization and interpretation. Such challenges in the field of computational vision present an ideal test bed for pattern recognition and machine learning algorithms. We apply new sampling techniques to image segmentation, investigating the different approaches for efficient large scale inference. Graphical models are used to learn object categorization from labeled data, providing a framework for integrating multiple sources of information.

 
Project titles:
 
Members:

 - Patrick Pletscher
 - Alexander Vezhnevets

Computational Biology

   
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With the advent of high throughput methods for genomics and proteomics, automated tools for processing and analysis of the large amounts of data is highly necessary. Our efforts are focused on using machine learning and statistical techniques, to solve complex problems arising in biological and medical context. We emphasize on applications of kernel-based analysis, network inference and probabilistic modeling. The research is inspired by real-world problems and data, that arise from our established collaborations with biologists and medical scientists. In collaboration with other groups, we are further interested in using the predictions of our machine learning algorithms to guide biological experiments.

 
Project titles: 
 
Members:

 - Xenofon Floros
 - Alberto Giovanni Busetto
 - Cheng Soon Ong

Auditory Scene Analysis

   
phonak_prj

The human auditory system selects relevant sounds from noise and irrelevant acoustic input. For hearing impaired persons, this ability is often significantly reduced. Furthermore, resolution in time and frequency is degraded, which makes it difficult to accurately locate a source. In collaboration with Phonak AG, we develop methods to analyze acoustic scenes and hearing instrument wearers' needs, with the goal of optimal adaptive control of the hearing instrument. Our current research focuses on hierarchical classification, component analysis, unsupervised and semi-supervised online learning, and model based signal processing.

 
Project titles:
 
Members:

 - Tomas Dikk
 - Christian Sigg

Foundations of Machine Learning

   
ml_foundation_image

We study the statistical and algorithmic principles behind learning from data. One key issue is the notion of complexity, and how to control it while finding a model that is in agreement with the observed measurements. We focus our efforts on structured data, investigating approaches such as clustering, graphical models and dynamical systems. A major effort of our algorithmic and modeling work is devoted to quantify the robustness of the learned structures, i.e., to provide the data analyst with uncertainty estimates of models and methods.

 
Project titles:

- Inference on discrete structures
- Experiment design in system biology
- Discriminative methods for structured data

 
Members:

 - Ludwig Busse
 - Alberto Giovanni Busetto
 - Patrick Pletscher
 - Cheng Soon Ong

 

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© 2012 ETH Zurich | Imprint | Disclaimer | 16 November 2011
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